The patients in the sepsis group with AKI stage 2–3 showed a median hepcidin serum concentration of 49.0 nmol/L (IQR 23.0–70.8) versus 37.0 nmol/L (IQR 20.5–64.0) in sepsis patients with AKI 0 and AKI stage 1 (Fig 4). Here, HAMP is linked to acute kidney injury.