Conversely, in GBM, mesothelioma (MESO), cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), LUAD and Pancreatic adenocarcinoma (PAAD), overexpression of HOTAIR was associated with longer OS, suggesting a potentially protective role of HOTAIR in these specific cancer contexts. The gene discussed is HOTAIR; the disease is pancreatic adenocarcinoma.