Overexpression of Rab31 in cancer-associated fibroblasts (CAFs) enhances cell migration in an HGF/MET-dependent manner in colon cancer cells, indicating a key role for Rab31-expressed CAF in the colon cancer cell migration by mediating paracrine secretion of HGF (Yang et al. 2020). The gene discussed is HGF; the disease is colonic neoplasm.