Additionally, alterations in ferroptosis vulnerability induced by RAB13 are found to be dependent on GPX4 expression (Jacob et al. 2013).A previous study has shown that, consistent with the attenuation of mTORC1 activity, knockdown of Rab32 suppresses cell proliferation while increases the nuclear localization of TFEB and lysosomal biogenesis in HCC cells (Drizyte-Miller et al. 2020). The gene discussed is GPX4; the disease is hepatocellular carcinoma.