blueberry leaves (PBL) can rapidly improve the viability of NAFLD cell models and further found that the protein expressions of Bcl-2 and Caspase-3 were in line with the expected mechanism of action of PBL, finally revealing that the multi-target mechanism of PBL against NAFLD is closely related to apoptosis pathways. This evidence concerns the gene CASP3 and metabolic dysfunction-associated steatotic liver disease.