STAT6 and neoplasm: Among them, some transcription factors have been reported to mediate the EMT process, such as TBL1XR1, STAT6, ETV6, and SMARCA4, indicating their potential to regulate VM and promote tumor invasion (Fararjeh and Liu, 2019; Zhao et al., 2019; Chen et al., 2023; Xu et al., 2023).