In earlier research, we established and evaluated a severe pneumonia model in high-load MP-infected mice (Wu et al., 2023a) and showed that YQDP regulates the TLR2/MyD88/NF-κB signaling pathway, Aquaporin5 (AQP5), and Mucin 5ac (MUC5ac) to regulate SMPP (Wu et al., 2023b; Qi et al., 2023). The gene discussed is MUC5AC; the disease is pneumonia.