When the Wnt/β-catenin pathway was activated in CRC, the expression of CAF-derived exosomal miR-92a-3p rose and directly suppressed FBXW7 and MOAP1 expression to prevent mitochondrial apoptosis, causing CRC cells to produce stem cell characteristics (Hu et al., 2019). This evidence concerns the gene FBXW7 and colorectal carcinoma.