Downregulation or loss of NDUFA1 expression is a known consistent feature of basal cell carcinoma (Mamelak et al., 2005), while reduced expression of IL13RA1 has been associated with apoptosis and promotion of epithelial to mesenchymal transition (EMT) in pancreatic cancer (Shi et al., 2022). This evidence concerns the gene IL13RA1 and familial pancreatic carcinoma.