KCND2 and Familial prostate cancer: For example, Kcnd2, Tspan12, Ing3 and Cped1 located on Chromosome six are known to promote proliferation of breast cancer cells (Yang et al., 2023), be a critical factor for cancer associated fibroblast mediated invasion (Otomo et al., 2014), used as a potential biomarker for CRC/breast cancer (Kim and Lee, 2022; Li et al., 2023) or confer oncogenic effects in prostate cancer (Zhu et al., 2023) respectively.