The activity of c‐MET‐downstream kinases, ERK 1⁄2, and AKT/S6K might also be related to enhanced cell survival and proliferation in 786‐O/S and Caki‐2/S cells, as previous studies have reported,42 also concerning pathogenesis and sunitinib resistance in RCC.43, 44, 45. The gene discussed is RPS6KB1; the disease is renal cell carcinoma.