CXCL8 and hepatocellular carcinoma: There were significant differences in IL-8 expression between the CHB group and the HI, SL-HBV, DN and HCC groups (P = 0.001; P = 0.011; P = 0.000; P = 0.000); moreover, the LC group and the HI, DN and HCC groups were significantly different (P = 0.011; P = 0.000; P = 0.000) (Fig. 1G).