In the preoperative HCC group, the FGF-2, IL-4, and IL-8 levels were significantly lower than those in the CHB group (Fig. 2A, B, F); the IL-8 expression was also significantly lower than that in the LC group (Fig. 2F); and the IL-10 expression was significantly greater than that in the LC group (Fig. 2C). Here, CXCL8 is linked to laryngotracheoesophageal cleft.