EDEM3 and fatty liver disease: These genes include DEMA (maintaining glucose homeostasis), SELENOM (involved in hepatic steatosis, inflammation, lipid metabolism, and fatty acid oxidation, is associated with hepatocellular degeneration and carcinoma), EDEM3 (controls the uptake of very low-density lipoprotein and plasma triglycerides), and ABCAA (involved in lipid metabolism).