The goose-specific genes were enriched in the process "Pathways in cancer", including Insulin resistance (6 genes; typically, MLXIP), Nonalcoholic fatty liver disease (10 genes; typically, NDUFB10 and MLXIP), HCC (11 genes; typically, IGF2 and E2F1); NF-kappa B signaling pathway (12 genes; typically, LY96). This evidence concerns the gene E2F1 and metabolic dysfunction-associated steatotic liver disease.