Other infection-related factors may intervene in IBM, such as activation of NLRP3 inflammasome, heat shock proteins (HSP), ribosomal proteins, or molecular mimicry with a mycobacterial protein guanylate-binding protein 2 (GBP2) with antiviral and anti-tuberculous functions [5, 60]. The gene discussed is GBP2; the disease is inclusion body myositis.