LOXL1 and colorectal carcinoma: LOXL1-AS1 can up-regulate the expression of HK2 and accelerate the progress of CRC by adsorbing miR-1224-5p/miR-761 [20]. Yang et al. [17] confirmed the binding of LOXL1-AS1 to miR-28-5p by luciferase reporter gene detection.