LOXL1 and retinoblastoma: In RB cell line, knockdown of LOXL1-AS1 gene inhibits the migration and invasion of RB cells. In the model of RB xenotransplantation, knocking down LOXL1-AS1 can also significantly inhibit tumor growth and promote tumor cell apoptosis, indicating that LOXL1-AS1 is expected to be the basis for clinical treatment of RB [68].