With respect to increased risk of asthma, blood genes again had the largest relative effect sizes in males (BAG6, CCNG, CRAT, PTPA, and FAM89B), with female training genes exhibiting the largest effects in ATP6V1G2 in the vastus lateralis, ENDOU in white adipose, and CCNF in blood. The gene discussed is FAM89B; the disease is asthma.