While our in-depth investigation primarily focused on the membrane proteins of S. aureus as a microbial component responsible for interacting with epithelial CD47, additional research is necessary to uncover the specific surface proteins binding to CD47 in other pneumonia-causing pathogenic bacteria, such as S. pneumoniae, Haemophilus influenzae, and Streptococcus hemolyticus. This evidence concerns the gene CD47 and pneumonia.