Thus, the aim of this study was to determine the relationship between interleukin (IL)-1β, IL-6, IL-10, interferon (IFN)α inflammatory cytokines and the psychological stress-related markers, glucocorticoid receptor-α (GRα), and sAA gene expression levels in saliva samples obtained from healthy implants and peri-implantitis patients. The gene discussed is IL1B; the disease is Peri-Implantitis.