SD: Standard deviation; CDT: Catheter-directed thrombolysis; USCDT: Ultrasound-facilitated catheter-directed thrombolysis (USCDT); BMI: Body mass index; DVT: Deep vein thrombosis; PE: Pulmonary embolism; CKD: Chronic kidney disease; CHF: Congestive heart failure; US: Ultrasound; BNP: B-type natriuretic peptide; hs troponin: High-sensitivity troponin. The gene discussed is NPPB; the disease is deep vein thrombosis.