focuses on the activation of SIRT1 signaling by RSV, leading to the reduction in the accumulation of neutrophils, TNF-α expression, and myocardial cell apoptosis, thereby conferring protection against septic myocardial injury through the measurement of TNF-α, myeloperoxidase (MPO), SIRT1, acetylated-FoxO1, and Bcl-2 levels in sepsis model mice (164). This evidence concerns the gene FOXO1 and Sepsis.