Additionally, CD4+ T lymphocytes exhibit a regulatory response represented by Treg phenotype, involving transcription factor forkhead box P3 (FOXP3) and TGF-β, crucial for immune homeostasis and autoimmunity prevention through secretion of anti-inflammatory cytokines like IL-10 and TGF-β (31–33). This evidence concerns the gene TGFB1 and Autoimmunity.