In contrast, low expression of ATP7B was associated with ABC transporters, glycosylphosphatidylinositol GPI anchor biosynthesis, maturity-onset diabetes of the young, pantothenate and COA biosynthesis, biosynthesis of unsaturated fatty acid, alpha-linolenic acid metabolism, sulfur metabolism, ascorbate and aldarate metabolism, butanoate metabolism, porphyrin, and chlorophyll metabolism, starch and sucrose metabolism, and other glycan degradation (Figure 6D). The gene discussed is ABCG2; the disease is type 2 diabetes mellitus.