The expression of Piezo1 was higher in high invasive gliomas than in low invasive gliomas, and its immunofluorescence images showed that Piezo1 was distributed at the adhesion spots mediated by integrins and FAK activation, indicating that Piezo1 may be related to the integrin-adhesion spot pathway and thus participate in the adhesion and migration of tumors (Chen et al., 2018). This evidence concerns the gene PTK2 and central nervous system cancer.