Besides, fluid shear stress and Yoda1 synergistically activate Piezo1 in prostate cancer cells by increasing the proportion of early S/S/G2/M phase in the cell cycle through the activation of YAP/TAZ, while transplanted Piezo1-silenced prostate cancer cells failed to proliferate in vivo (Kim O-H. This evidence concerns the gene PIEZO1 and prostate carcinoma.