Furthermore, it indicated that IL-17 signaling pathway (hsa04657) and Fluid shear stress and atherosclerosis (hsa05418) pathways are upregulated in both males and females with AD, while Glutamatergic synapse (hsa04724) and Oxytocin signaling pathway (hsa04921) are downregulated in both sexes. This evidence concerns the gene IL17A and atherosclerosis.