Notably, SLC1A7 was upregulated in M-AD vs. M-controls and downregulated in F-AD vs. F-controls in both CA1 and CA3 subfields, while TMEM10, MOG, and MAL were upregulated in F-AD vs. F-controls and downregulated in M-AD vs. M-controls in the CA3 subfield. The gene discussed is OPALIN; the disease is Alzheimer disease.