ERCC5 and sarcopenia: Interestingly, α‐ketoglutarate (aKG), which was elevated locally in Xpg−/− muscle upon DR (Figure 5F), has been recently implicated in extension of lifespan and compression of morbidity [S18], opening opportunities for further research for assessing and modulating aKG levels systemically for counteracting accelerated aging and sarcopenia.30