We therefore repeated the analysis, only considering variants in genes classified as definitive DCM-gene (BAG3, DES, FLNC, LMNA, MYH7, PLN, RBM20, SCN5A, TNNC1, TNNT2, TTN) and genes with strong (DSP) or moderate evidence of involvement in DCM (ACTC1, ACTN2, JPH2, NEXN, TNNI3, TPM1, VCL) [22]. The gene discussed is BAG3; the disease is familial dilated cardiomyopathy.