We therefore repeated the analysis, only considering variants in genes classified as definitive DCM-gene (BAG3, DES, FLNC, LMNA, MYH7, PLN, RBM20, SCN5A, TNNC1, TNNT2, TTN) and genes with strong (DSP) or moderate evidence of involvement in DCM (ACTC1, ACTN2, JPH2, NEXN, TNNI3, TPM1, VCL) [22]. Here, PLN is linked to familial dilated cardiomyopathy.