In contrast, higher levels of interleukin 6 receptor (IL6R) (OR = 0.96, 95% CI: 0.95–0.98, P = 2.21E-07), FES proto-oncogene, tyrosine kinase (FES) (OR = 0.68, 95% CI: 0.59–0.79, P = 6.40E-07), switching B cell complex subunit SWAP70 (SWAP70) (OR = 0.93, 95% CI: 0.91–0.96, P = 8.15E-06), and placental growth factor (PGF) (OR = 0.69, 95% CI: 0.59–0.82, P = 1.64E-05) were associated with decreased risk of CHD (Supplementary Table S2). The gene discussed is PGF; the disease is coronary artery disorder.