For example, SLP1, sortilin, and EPHA2 are specifically distributed in the nervous system and function in neurological diseases [24–26]; CCNT1 is related to HIV infections [27]; while TNFRs (TNFR1, TNFR2) are associated with inflammatory regulation, of which TNFR2 usually involves anti-inflammatory responses [28, 29]. The gene discussed is TNFRSF1B; the disease is nervous system disorder.