In another study, XRN1 was reported to be involved in the turnover of several tumor-suppressive miRNAs (miR-363, miR-101, and miR-128) at the precursor miRNA level by forming a processing complex with IFIT5, which is an IFNγ-induced EMT-stimulating gene (Fig. 6)15. Here, XRN1 is linked to neoplasm.