In this study, pre-PLR was related to the gender, T stage, clinical stage, ECOG, pathological type, pre-HGB, pre-CRP, pre-LMR and pre-ALB of patients with NPC, which was consistent with the conclusion of JIANG et al.31 who studied 247 patients with NPC who received IMRT. This evidence concerns the gene CRP and nasopharyngeal carcinoma.