In embryonal tumors, the topmost DE genes included many ribosome-associated genes like RPS2, RPLP1, and RPL13A as well as histone H3.3 related genes like H3F3A and H3F3B. Ependymomas had 1024 downregulated and 1213 upregulated genes compared to non-tumor tissue. The gene discussed is RPLP1; the disease is ependymoma.