AR and posterior cortical atrophy: Gene set enrichment analyses (GSEA) using hallmark gene sets revealed that while AR-V7– and AR-FL–activated genes were similarly enriched for the classic androgen response pathway in most models, genes activated by AR-V7 or ARv567es in all the models were specifically enriched for the EMT functions, a pathway not activated by AR-FL in any of these PCa models (Figure 2F).