VTCN1 and neoplasm: Together, these data suggest B7-H4 tumor cell expression in EMT6 tumors contributes to immunotherapy resistance by altering tumor susceptibility to ICI, and as a side observation, notes a possible and interesting strain-specific difference in B7-H4 expression between BALB/c and C57BL/6 mice which could be important to others in the field for future mechanistic studies in preclinical models.