In addition, histamine is found to promote IL‐10 and inhibit TGF‐α in OVA‐induced asthma in mice, thereby reducing the total number of cells in bronchoalveolar lavage fluid (BALF) and the number of inflammatory factors such as IL‐4, IL‐5, and IL‐13 in lung tissue.99 This evidence concerns the gene IL10 and asthma.