This trend is consistent with clinical research findings that chronic periodontitis patients have higher concentrations of antimicrobial peptide LL-37 (cathelicidin LL-37) in their saliva and gingival crevicular fluid compared to healthy subjects.11 CAMP is the murine ortholog of LL-37 and exhibits similar antimicrobial activity against pathogens in vitro.3 Although the concentration of CAMP in rat saliva after intranasal immunisation was lower than the minimum bactericidal concentration for periodontal disease pathogens, CAMP plays a critical role in oral homeostasis. Here, CAMP is linked to chronic periodontitis.