XPC and melanoma: The XPC rs2228000 CT (OR = 0.15 95%CI 0.07–0.29; p < 0.001) and TT (OR 0.11; 95% CI 0.03–0.37; p < 0.001) had decreased melanoma risks compared to the reference genotype (CC). Analogously, XPC G1475A_AG genotype and XPD rs238406_AC genotype were associated with significantly increased risk of melanoma (OR 3.54; 95% CI 1.18–12.6; p < 0.05 and OR 2.38; 95% CI 1.14–4.96; p < 0.05, respectively) in comparison with the reference genotypes