This suggested that the presence of TgAb reduces Tg measured by all methodologies—a TgAb-lowering effect that was supported by the inverse log TgAb/Tg relationships seen with all methods for the TgAb + HY patient group (Fig. 6), and the rapid Tg decline following a de novo TgAb appearance in a DTC patient with progressive DMD (Fig. 3F). Here, TG is linked to Duchenne muscular dystrophy.