NELL1 and neoplasm: In recent years, studies on NELL-1 positive malignancy-associated MN have found that the expression of NELL-1 was observed in tumor and kidney specimens from patients with breast cancer, lymphoid follicle carcinoma and esophageal cancer (9, 42), but no study has confirmed a clear mechanism of action for NELL-1 in MN associated with malignant tumors.