The rest of the diffuse and anaplastic astrocytoma, IDH-wild-type, which displayed a passive clinical course, had been low-grade gliomas, which include pilocytic astrocytoma, glioneuronal tumors, and diffuse gliomas of the pediatric type, according to more accurate molecular analyses, including DNA methylation profiling [12]. Here, IDH2 is linked to anaplastic astrocytoma.