IL6 and rheumatic disorder: Xie et al. suggest that increased uric acid levels suppress neutrophil adhesion and extravasation in mice with SARS-CoV-2 inflammation or infection [15]. In addition, IL-6 levels are higher in patients with rheumatic diseases such as gout, increasing the number of recruited lymphocytes to the synovial fluid when infected with SARS-CoV-2, leading to greater inflammation and worsening outcomes [1].