We found that CAF subtypes 0 (BTG1+ CAF), 2 (CFD+ CAF), and 4 (IGFBP7+ CAF) were more abundant in the tumor than the normal, while CAF subcluster 1 (OGN+ CAF), 3 (C1R+ CAF), 5 (MFAP5+ CAF), and 6 (SFRP4+ CAF) were more abundant in the normal than the tumor (Figure 3A). This evidence concerns the gene SFRP4 and neoplasm.