SLURP1 and posterior cortical atrophy: Figure 1A illustrates the presence of 12 upregulated proteins that exhibited differential expression in the PCa group. Moreover, we conducted an analysis on the expression of SLURP1 across various cohorts, as illustrated in Figure 1B. The SLURP1 protein exhibited a progressive elevation in the urine samples obtained from individuals with normal prostate function, BPH, and PCa. Notably, a statistically significant distinction (P<0.05) was observed when comparing the SLURP1 protein levels in urine between patients diagnosed with BPH and those with PCa.