CTLA4 and neoplasm: To confirm that this similarity is maintained with a different combination ICT, (anti-CTLA-4 and anti-PD-L1), we performed bulk TCRβ sequencing on tumours from treated animals (Supp Figure S3(d)) and similarly found that TCRβ repertoires in tumours were highly related within animals, but not between animals (Supp Figure S3E).