In glioblastoma, the fusion of FGFR3 with transforming acidic coiled-coil containing protein (TACC3) results in FGFR3-TACC3, which activates MAPK and extracellular signal-regulated kinase (ERK) signaling, facilitates in vitro transformation and increases cell proliferation [61]. The gene discussed is FGFR3; the disease is glioblastoma.