TP53 and cancer: KEGG results in BT549 cells were enriched in the well-known and universal pathways in cancer, including apoptosis, autophagy, ferroptosis, transcriptional dysregulation of MAPK, IL17 and P53 signaling pathways in cancer (Fig. 3D); the similar results, excluding autophagy and ferroptosis, were found in A549 cells (Fig. 3E).