TLR2 and gastric neoplasm: Researchers found that TLR2 mRNA and protein expression levels were elevated in mouse gastric cancer models, GC cell lines, and gastric tumors in human GC and that TLR2 overexpression was associated with high histologic grade, microvascular invasion, and cell adhesion and was a poor prognostic factor.193, 194, 195, 196, 197