There were statistically significant differences in age, gender, race, education, SBP, DBP, BMI, waist circumference, hypertension, diabetes, smoking status, serum Albumin, serum Blood Urea Nitrogen, serum Uric Acid, eGFR, ALT, AST, ACR among the DII tertiles (-5.2811–0.8623, 0.8628–2.63771, 2.6378–5.79464). The gene discussed is GPT; the disease is diabetes mellitus.