To determine the effectiveness of scFv‐IL‐13Rα2 CAR‐T cells treatment to IL‐13Rα2 positive glioma xenografts in NOG mice, U251, U251‐IL‐13Rα2 knock down, U87MG and U87MG IL‐13Rα2 knock down glioma cells were subcutaneously implanted in NOG female mice. Here, IL13RA2 is linked to glioma.