MAP3K11 and infection: Streptococcus gordonii, Fusobacterium nucleatum and Porphyromonas gingivalis synergistically promote the formation and proliferation of plaque biofilms, inhibit the growth of dendritic cells [50], and cause peripheral blood infection via bacterial tyrosine (BY) kinase (Ptk1), which is an important part of the signalling pathway that controls the synergistic interaction between Porphyromonas gingivalis and Streptococcus gordonii [51].