They further showed that the aggravation of Mav-PI with a suppressed Th17 immune response was more prominent when allergic asthma was induced after M. avium infection than when asthma preceded it, and the comorbid allergic asthma in Mav-PI showed reduced disease progression over time, accompanied by a diminished degree of goblet cell hyperplasia with reduced IL-13 production. This evidence concerns the gene IL13 and asthma.