It is noteworthy that, among the mice that were not induced to AKI, macrophage infiltration into the renal interstitium, expressed as the mean number of Mac-2 + cells, was higher in the obese group than in the normal group (8.4 ± 1.7 vs. 1.0 ± 0.24 cells/0.087 mm2; P < 0.05). Here, LGALS3 is linked to acute kidney injury.