In addition, up-regulation of SPTBN2 in PAAD was associated with increased expression of chemokine receptors (CXCR5, CCR10), major histocompatibility complex (MHC) molecules (TAP2, TAPBP), immunosuppressive molecules (TGFB1), and immunostimulatory molecules (TNFSF13, CD40, NT5E, and CD276). Here, TAPBP is linked to pancreatic adenocarcinoma.